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Home Alzheimer
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Alzheimer

What do we offer?

  • icono de laboratorioDetection of genes involved in predisposition to : Late-onset Alzheimer
  • icono de asesoramiento facultativoCounselling by a specialist before and after the analysis
  • icono de la muestraSample type: Collection of saliva through an oral swab
  • icono de tiempoResults in: 14 days*
  • 230 **
  • * Labour days counting from reception of the sample at the laboratory.
    ** Shipping charges included in peninsular Spain. Not included in Islands.

elige tu test genético

Why should you request this service?

What is the purpose of this analysis?

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  • To detect the polymorphisms responsible for the disease, because an early detection allows your doctor to establish your risk of developing Alzheimer's disease. It permits the specialist to show you the specific measures to slow the development of the disease.

  • To give you the necessary tools to delay or even prevent the onset of the disease if you are asymptomatic and you have a first-degree relative who already developed the disease.

Should you do it?

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  • You have progressive signs of dementia: to support the diagnosis of Alzheimer's.

  • You have relatives with Alzheimer's: In order to determine the genetic risk of contracting the disease.

How does it work?

  1. elige tu test genético
    Choose your analysis and a healthcare professional will contact you in 48 hours
  2. frotis bucal para análisis
    You will receive a sample collector kit at home that will be picked up by a courier
  3. instrucciones de uso
    One of our partner labs will proceed to make the analysis
  4. instrucciones de uso
    Your healthcare professional will present your results by videoconference
go further

To go further:


Subtitles available in both English and French

Do you need more information?

  • What are the genes studied and what does it mean?>
      GENE OMIM or reference RELATED DISEASE SYNDROME
      APOE 155541
      601665
      Alzheimer Late on-set type 2 Alzheimer
  • How to interpret the results?>
      POSITIVE NEGATIVE
      A genetic variant predisposing to the disease has been detected:
      E2/E4 o E3/E4 o E4/E4
      No genetic variants predisposing to the disease have been detected.
      Increased risk Same risk as random people
  • Sensitivity and Specificity>

      The analysis of this gene is carried out using the PCR (Polymerase Chain Reaction) technique. Moreover, the results are studied by direct sequencing and subsequent capillary electrophoresis. These molecular biology techniques are commonly used in the field of molecular genetics and exhibit high sensitivity and specificity when using specific primers for each analyzed polymorphism. The reliability of our genetic studies is close to 100%, we apply quality processes certified by competent national and international organizations.

  • Guidelines>
    • Borroni, B., et al. The effect of APOE genotype on clinical phenotype in Alzheimer disease. Neurology 68: 624 only, 2007.
    • Wolk, D. A., et al. Alzheimer's Disease Neuroimaging Initiative. Apolipoprotein E (APOE) genotype has dissociable effects on memory and attentional-executive network function in Alzheimer's disease. Proc. Nat. Acad. Sci. 107: 10256-10261, 2010.
    • Kunz, L., et al. Reduced grid-cell-like representations in adults at genetic risk for Alzheimer's disease. Science 350: 430-433, 2015.
    • NIH Publication No. 15-6424 (2015). Alzheimer’s Disease Genetics. FACT SHEET
    • Online Mendelian Inheritance in Man, OMIM®. McKusick- Nathans Institute of Genetic Medicine, Johns Hopkins University (Baltimore, MD), {24/04/2018}. World Wide Web URL: https://omim.org/

Any questions?

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