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Home Lactose
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Lactose

What do we offer?

  • icono de laboratorioDetection of genes involved in predisposition to : Intolerance to Lactose
  • icono de asesoramiento facultativoCounselling by a specialist before and after the analysis
  • icono de la muestraSample type: Collection of saliva through an oral swab
  • icono de tiempoResults in: 14 days*
  • 230 **
  • * Labour days counting from reception of the sample at the laboratory.
    ** Shipping charges included in peninsular Spain. Not included in Islands.

elige tu test genético

Why should you request this service?

What is the purpose of this analysis?

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  • To detect a possible predisposition to lactose intolerance. Lactase is a very fragile and vulnerable intestinal enzyme. If you suffer from lactose intolerance, you should completely avoid its ingestion. If your intolerance is undiagnosed and you continue to consume products containing lactose, the intestinal lesion worsens, resulting in nutrient malabsorption and a vicious cycle that is difficult to reverse.

  • If the result is negative, your predisposition to develop lactose intolerance is ruled out, so the specialist should look for another explanation for your symptoms.

  • The main interest of this analysis is to be able to determine if it is an intolerance due to genetic factors or if the symptoms result from another pathology.

Should you do it?

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  • You have a family history
  • You don’t have any family history:
    • You have symptoms of digestive intolerance.
    • You are likely to have one of the associated diseases.
    • You have an autoimmune disease.
    • You reserve a doubt about an established diagnosis.

How does it work?

  1. elige tu test genético
    Choose your analysis and a healthcare professional will contact you in 48 hours
  2. frotis bucal para análisis
    You will receive a sample collector kit at home that will be picked up by a courier
  3. instrucciones de uso
    One of our partner labs will proceed to make the analysis
  4. instrucciones de uso
    Your healthcare professional will present your results by videoconference
go further

To go further:


Subtitles available in both English and French

Do you need more information?

  • What are the genes studied and what does it mean?>
      GEN OMIM or reference RELATED DISEASE SYNDROME
      MCM6 601806 MCM6 contains two regulatory regions of LCT, the current gene for lactase protein.
      The decrease in digestive enzyme lactase levels makes it impossible to digest lactose in the intestine and is caused by a decrease in the transcription of the LCT gene encoding this enzyme.
      Lactose intolerance
  • How to interpret the results?>
      POSITIVE NEGATIVE
      MCM6 gene:
      POLYMORPHISM c.-13910C>T
      POLYMORPHISM c.-22018G>A
      with the homozygous variants C and G, respectively present simultaneously
      NO genetic variant has been identified that carries a higher susceptibility to the disease.
      Higher risk than the general population Same risk as random population
  • Sensitivity and Specificity>

      The analysis of this gene is carried out using the PCR (Polymerase Chain Reaction) technique and reaction products are studied by reverse hybridization with specific sequence probes (SSOP). Moreover, the results are studied by direct sequencing and subsequent capillary electrophoresis. These molecular biology techniques are commonly used in the field of molecular genetics and exhibit high sensitivity and specificity when using specific primers for each analyzed polymorphism. The reliability of our genetic studies is close to 100%, we apply quality processes certified by competent national and international organizations.

  • Guidelines>
    • Vesa TH. et al.; Lactose Intolerance. Journal of the American College of Nutrition, Vol. 19, No. 2, 165S–175S (2000)
    • Mattar R. et al.; Lactose intolerance: diagnosis, genetic, and clinical factors. Clinical and Experimental Gastroenterology 2012:5 113–121
    • Online Mendelian Inheritance in Man, OMIM®. McKusick- Nathans Institute of Genetic Medicine, Johns Hopkins University (Baltimore, MD), {24/04/2018}. World Wide Web URL: https://omim.org/

Any questions?

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