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Home Diabetes
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What do we offer?

  • icono de laboratorioDetection of genes involved in predisposition to : Diabetes mellitus type 2
  • icono de asesoramiento facultativoCounselling by a specialist before and after the analysis
  • icono de la muestraSample type: Collection of saliva through an oral swab
  • icono de tiempoResults in: 21 days*
  • 260 **
  • * Labour days counting from reception of the sample at the laboratory.
    ** Shipping charges included in peninsular Spain. Not included in Islands.

elige tu test genético

Why should you request this service?

What is the purpose of this analysis?

  • To show you the genetic burden of these common multifactorial diseases and that you can relate them to environmental factors.

  • To help you discover the mechanisms responsible for obesity, diabetes or cardiovascular disease in each case to provide you with adapted and personalized treatments.

  • To detect your susceptibility to develop the disease and then apply preventive measures on you or your family members in case of risk.

Should you do it?

  • You have a family history:

    • You have a family history:
  • You suffer from DIABETES:

    • You suffer from a disfunction in carbohydrate metabolism.
    • You have high levels of glucose, insulin, or glycosylated hemoglobin.
    • Carbohydrates easily make you put on weight.
    • You suffer from obesity, (mainly abdominal obesity) and you want to prevent the development of diabetes.
  • You want to improve your lifestyle or adapt your treatment.

How does it work?

  1. elige tu test genético
    Choose your analysis and a healthcare professional will contact you in 48 hours
  2. frotis bucal para análisis
    You will receive a sample collector kit at home that will be picked up by a courier
  3. instrucciones de uso
    One of our partner labs will proceed to make the analysis
  4. instrucciones de uso
    Your healthcare professional will present your results by videoconference
go further

To go further:

Subtitles available in both English and French

Do you need more information?

  • What are the genes studied and what does it mean?>
      IL6 147620 It causes a chronic low-grade inflammation of adipose tissue, induces insulin resistance because it alters its receptor and promotes the development of type 2 diabetes (adult). TYPE 2 DIABETES: ECONOMIC GENES
      PPARG 601487 The ancestral gene is not suitable for contemporary foods such as refined foods (flours and sugars) or processed and saturated fats that promote fat formation and insulin resistance. This gene also complicates the burning of calories. In addition, this gene is the main target of one of the antidiabetic drugs, a good knowledge of this gene allows a personalized treatment.
      FABP2 134640 It facilitates the absorption of dietary fat in the intestine and alters its oxidation, promoting insulin resistance and increasing the risk of atherosclerosis.
      ADIPOQ 605441 It induces insulin resistance, which hinders the metabolism of carbohydrates and promotes the development of obesity and type 2 diabetes.
      IRS1 147545 It causes insulin resistance and therefore a high risk of diabetes because it directly affects the insulin receptor.
  • How to interpret the results?>
      Gene FABP2: POLYMORPHISME c.163A>G (p.T55A)
      Gene ADIPOQ: POLYMORPHISME c.214+62G>T
      Gene PPARG: POLYMORPHISME c.34C>G (p.P12A)
      Gene IRS1: POLYMORPHISME c.2911G>A (p.Gly971Arg)
      Gene IL6: POLYMORPHISME c.116-121C>G
      No genetic variants predisposing to the disease have been detected.
      Increased risk Moderate risk
  • Sensitivity and Specificity>

      The analysis of this gene is carried out using the PCR (Polymerase Chain Reaction) technique. Moreover, the results are studied by direct sequencing and subsequent capillary electrophoresis. These molecular biology techniques are commonly used in the field of molecular genetics and exhibit high sensitivity and specificity when using specific primers for each analyzed polymorphism. The reliability of our genetic studies is close to 100%, we apply quality processes certified by competent national and international organizations.

  • Guidelines>
    • Aranceta-Bartrina, J., et al. Prevalencia de obesidad general y obesidad abdominal en la población adulta española (25–64 años) 2014–2015: estudio ENPE. Rev Esp Cardiol. 2016;69:579-87 - Vol. 69 Núm.06 DOI: 10.1016/j.recesp.2016.02.010
    • Strandberg,L., et al.; Interleukin-1 System Gene Polymorphisms Are Associated with Fat Mass in Young Men, The Journal of Clinical Endocrinology & Metabolism, Volume 91, Issue 7, 1 July 2006, Pages 2749–2754,
    • Goyenechea et al, 2007. Impact of interleukin 6 -174G>C polymorphism on obesity-related metabolic disorders in people with excess in body weight. Metabolism 56(12):1643-8.
    • Stephens et al, 2007. Association between plasma IL-6, the IL6 -174G>C gene variant and the metabolic syndrome in type 2 diabetes mellitus. Mol Genet Metab 90(4):422-8.
    • Jellema et al, 2003. Gly972Arg variant in the insulin receptor substrate-1 gen and association with Type 2 diabetes: a meta-analysis of 27 studies. Diabetologia 46:990-995.
    • Thameem et al, 2012. The Gly(972)Arg variant if human IRS1 gene is associated with variation in glomerular filtration rate likely through impaired insulin receptor signaling. Diabetes 61:2385-93.
    • Online Mendelian Inheritance in Man, OMIM®. McKusick- Nathans Institute of Genetic Medicine, Johns Hopkins University (Baltimore, MD), {24/04/2018}. World Wide Web URL:

Any questions?

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