This site uses both its own cookies and third-party cookies in order to obtain statistical data on the browsing activity of its users. You accept these cookies by continuing to browse the Portal or by clicking ACCEPT You can find information on how to enable/disable browser cookies reading our Cookie Policy

This site uses both its own cookies and third-party cookies (files which are installed on the user’s device and which record browsing information) in order to obtain statistical data on the browsing activity of its users. By clicking ACCEPT or by continuing to browse the Portal, you accept that PROMETUM SPAIN S.L.U. may store and use these cookies. To find out more, please read our Cookie Policy where you can also find information on how to enable/disable browser cookies. ACCEPT

You will receive an e-mail with instructions to reset your password
Home Hypertension Risk
icono cardiologia.png

Hypertension Risk

What do we offer?

  • icono de laboratorioDetection of genes involved in predisposition to : Arterial hypertension
  • icono de asesoramiento facultativoCounselling by a specialist before and after the analysis
  • icono de la muestraSample type: Collection of saliva through an oral swab
  • icono de tiempoResults in: 14 days*
  • 330 **
  • * Labour days counting from reception of the sample at the laboratory.
    ** Shipping charges included in peninsular Spain. Not included in Islands.

elige tu test genético

Why should you request this service?

What is the purpose of this analysis?

  • To make you aware of the risk of hypertension, thus preventing the appearance of symptoms by changing environmental factors and at the same time minimizing the risk of developing associated pathologies in the kidneys, brain or heart.

  • It is particularly important to recommend this analyse to your family if you have high blood pressure to minimize the risk of developing the disease.

Should you do it?

  • You have a family history of hypertension.

How does it work?

  1. elige tu test genético
    Choose your analysis and a healthcare professional will contact you in 48 hours
  2. frotis bucal para análisis
    You will receive a sample collector kit at home that will be picked up by a courier
  3. instrucciones de uso
    One of our partner labs will proceed to make the analysis
  4. instrucciones de uso
    Your healthcare professional will present your results by videoconference
go further

To go further:

Subtitles available in both English and French

Do you need more information?

  • What are the genes studied and what does it mean?>
      ACE 106180 Coronary artery disease. Cardiovascular pathologies Risk of acute myocardial infarction
      Risk of hypertension
      Coronary changes
      ADRB2 109690 Metabolic syndrome
      Risk of hypertension
      GNB3 139130145500 Risk of progression to more severe hypertension
      NOS3 163729 Preeclampsia, coronary heart disease Risk of hypertension
  • How to interpret the results?>
      A genetic variant predisposing to the disease has been detected: No genetic variants predisposing to the disease have been detected.
      Increased risk Moderate risk
  • Sensitivity and Specificity>

      The analysis of this gene is carried out using the PCR (Polymerase Chain Reaction) technique. Moreover, the results are studied by direct sequencing and subsequent capillary electrophoresis. These molecular biology techniques are commonly used in the field of molecular genetics and exhibit high sensitivity and specificity when using specific primers for each analyzed polymorphism. The reliability of our genetic studies is close to 100%, we apply quality processes certified by competent national and international organizations.

  • Guidelines>
    • Saeed Mahmood, M, et al. Association of the angiotensin-converting enzyme (ACE) gene G2350A dimorphism with essential hypertension. J Hum Hypertens. 2003 Oct;17(10):719-23. OI:10.1038/sj.jhh.1001600.
    • Luft FC. Twins in cardiovascular genetic research. Hypertension. 2001 Feb;37(2 Pt 2):350-6.
    • Rudnicki M1, Mayer G. Significance of genetic polymorphisms of the renin-angiotensin-aldosterone system in cardiovascular and renaldisease. Pharmacogenomics. 2009 Mar;10(3):463-76.
    • Seidlerová J, Filipovský J, Mayer O Jr, Kučerová A, Pešta M. Association between endothelial NO synthase polymorphisms and arterial properties in the general population. Nitric Oxide. 2015 Jan 30;44:47-51
    • Vecoli C. Endothelial nitric oxide synthase gene polymorphisms in cardiovascular disease. Vitam Horm. 2014;96:387-406
    • Takeuchi F, Yamamoto K, Katsuya T, Sugiyama T, Nabika T, Ohnaka K, Yamaguchi S, Takayanagi R, Ogihara T, Kato N. Reevaluation of the association of seven candidate genes with blood pressure and hypertension: a replication study and meta-analysis with a larger sample size. Hypertens Res. 2012 Aug;35(8):825-31
    • Hager A, Bildau J, Kreuder J, Kaemmerer H, Hess J. Impact of genomic polymorphism on arterial hypertension after aortic coarctation repair. Int J Cardiol. 2011 Aug 18;151(1):63-8.
    • Guo X, Cheng S, Taylor KD, Cui J, Hughes R, Quiñones MJ, Bulnes-Enriquez I, De la Rosa R, Aurea G, Yang H, Hsueh W, Rotter JI. Hypertension genes are genetic markers for insulin sensitivity and resistance. Hypertension. 2005 Apr;45(4):799-803.
    • Online Mendelian Inheritance in Man, OMIM®. McKusick- Nathans Institute of Genetic Medicine, Johns Hopkins University (Baltimore, MD), {24/04/2018}. World Wide Web URL:

Any questions?

In compliance with the requirements of REGULATION (EU) 2016 / 679 OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL of 27 april 2016 on the protection of individuals with regard to the processing of personal data and the free movement of such data and repealing directive 95 / 46 / ec (general regulation of data protection), you are informed that ...