Genome

Full genome sequencing and interpretation to help you live a longer and healthier life

Genome is the complete genome sequencing service, interpretation and delivery of results by a genetic advisor, which will allow you to prevent diseases and improve your health. The service provides you with key information to adapt your lifestyle and advice on the necessary medical care based on your own genetics. Genome is aimed at helping any healthy, active person maintain their health.

15-20%

15-20% of cancers

are due to the inheritance of a genetic variant that predisposes to a tumor.

3% of the couples have a 25% risk

of having a child affected by a genetic disease.

15-20%

El 15-20% of sudden cardiac deaths

are due to gentic variations in genes responsible for the structure of the heart's muscle or heart rate.

6% of the population have an increase risk of developing thrombosis.

Aqquired factors like sedentary life or the lack of physical activity rises this risk.

3-5%

3-5% of hospital admissions in Europe

are due to adverse drug reactions.

Genome

We will inform you of your risks from 200+ diseases of genetic origin.
You will learn about 40+ diseases that could be transmitted to your children.
We will offer you data on 15 multifactorial diseases, which depend on genetics and environmental factors.
You will understand how your body will react to 110+ drugs based on your genetics.
We will provide you with information on +50 genetic traits related to diet, athletics, longevity, nutrition, metabolism and more.
You will learn about your ancestors.
A genetic counsellor approved by medmesafe will accompany you before and after the analysis by video consultation.

13 weeks

Spain

Saliva

Whole Genome Sequencing

13 weeks from reception of sample in laboratory

Only available in Spain

Collection of saliva.

Genome sequencing with Illumina HiSeq X Ten/Nova Seq with an average coverage of 30X (reference coverage in genome analysis).
99% analytical sensitivity for Single Nucleotide Variants and 97.6% for small insertions/deletions (6 bases).
Analysis and classification of variants with internal and external databases (ClinVar and Human Gene Mutation Database).
Variant screening carried out by an expert team with its own software developed for the detailed classification of variants.
For monitoring and quality control each sample is processed in Infinium QC Array-24 microarray (Illumina).

In 20% of patients there is a previous family history of cancer. It may be the result of coincidence, and similar lifestyles and environmental factors or genetic factors.

70–80% of tumors are unrelated to ancestry. Only 5 or 10% of tumors can be explained by a specific genetic alteration that directly causes the onset of the disease. In the remaining 15-20% of cases, there are familial characteristics that contribute to the onset.

Germ mutations occur in the ovule or sperm and are inheritable. In most inherited cancer syndromes, the chance of a child inheriting the family mutation is 50%.

It is important to note that being a carrier of a mutation is not synonymous with cancer, it means having a higher risk of developing one or more types of cancer. "

Source: https://seom.org/informacion-sobre-el-cancer/consejo-genetico

Worldwide, one in every 20 or 25 people is a carrier of the gene that produces CF (Cystic Fibrosis). This means that many people are carriers of the gene without being unaware of it, so the probability, proven in other countries by early-neonatal diagnosis, of an infant being born with CF (Cystic Fibrosis) is 1 in 2,500 to 3,000.”

Source: http://fqandalucia.org/fibrosis-quistica/que-es-la-fibrosis-quistica/

Each person has between 3 and 5 recessive genetic mutations, such as the one that causes cystic fibrosis. If both parents are carriers of the mutation, the chances of transmission are: